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Tsolo is a town in Mhlontlo Local Municipality in O.R.Tambo District of the Eastern Cape province of South Africa.

The town is some 42km north-west of Mthatha and 22 km south-west of Qumbu. The name, derived from Xhosa, is said to mean ‘pointed’, referring to the shape of hills there.<ref name=dsapn>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref>

Tsolo has two government hospitals, St Lucy's Hospital and Dr. Malizo Mpehle Memorial Hospital.<ref> Eastern Cape Dept of Health official website</ref>

Tsolo sections
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