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Syndrome::title    Medical::medical    Symptoms::author    Named::specific    Often::after    Disease::first

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A syndrome is a set of medical signs and symptoms that are correlated with each other and, often, with a specific disease. The word derives from the Greek σύνδρομον, meaning "concurrence".<ref name="Dorlands">{{#invoke:citation/CS1|citation |CitationClass=citation }}</ref> In some instances a syndrome is so closely correlated with a pathogenesis or etiology that the words syndrome, disease, and disorder end up being used interchangeably for them. This is especially true of genetically caused syndromes. For example, Down syndrome, Wolf–Hirschhorn syndrome, and Andersen syndrome are disorders with known pathogeneses, so each is more than just a set of signs and symptoms, despite the syndrome nomenclature. In other instances, a syndrome is not specific to only one disease. For example, toxic shock syndrome can be caused by various toxins; premotor syndrome can be caused by various brain lesions; and premenstrual syndrome is not a disease but simply a set of symptoms.

If an underlying genetic cause is suspected but not known, a condition may be referred to as an "association". By definition, an association shows that the collection of signs and symptoms occurs in combination more frequently than would be likely by chance alone.<ref name=association>{{#invoke:citation/CS1|citation |CitationClass=book }}</ref>

Syndromes are often named after the physician or group of physicians that discovered them or initially described the full clinical picture. Such eponymous syndrome names are examples of medical eponyms. Recently, there has been a shift towards naming conditions descriptively by symptoms or underlying cause rather than with eponyms. However the eponymous syndrome names often persist in common usage.


Syndrome sections
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