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Tests::medical    Category::other    Blood::serum    Serology::surveys    Sherris::semen    Response::baron

Serology is the scientific study of serum and other bodily fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum.<ref name=Sherris>{{#invoke:citation/CS1|citation |CitationClass=book }}</ref> Such antibodies are typically formed in response to an infection (against a given microorganism),<ref name=Baron>{{#invoke:citation/CS1|citation |CitationClass=book }}</ref> against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease).

Serological tests may be performed for diagnostic purposes when an infection is suspected, in rheumatic illnesses, and in many other situations, such as checking an individual's blood type.<ref name=Sherris /> Serology blood tests help to diagnose patients with certain immune deficiencies associated with the lack of antibodies, such as X-linked agammaglobulinemia. In such cases, tests for antibodies will be consistently negative.

There are several serology techniques that can be used depending on the antibodies being studied. These include: ELISA, agglutination, precipitation, complement-fixation, and fluorescent antibodies.

Some serological tests are not limited to blood serum, but can also be performed on other bodily fluids such as semen and saliva, which have (roughly) similar properties to serum.

Serological tests may also be used forensically, specifically for a piece of evidence (e.g., linking a rapist to a semen sample).


Serology sections
Intro   Serological surveys    See also   Notes and references   External links   

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