::Mycobacterium tuberculosis


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Mycobacterium tuberculosis is a pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of most cases of tuberculosis.<ref name=Sherris>{{#invoke:citation/CS1|citation |CitationClass=book }}</ref> First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface (primarily due to the presence of mycolic acid), which makes the cells impervious to Gram staining. The Ziehl-Neelsen stain, or acid-fast stain, is used instead. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, and chest radiographs.<ref name=Sherris/>

The M. tuberculosis genome was sequenced in 1998.<ref>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref>

Mycobacterium tuberculosis sections
Intro  Pathophysiology  Genome  Evolution  Genetics of Mycobacterium tuberculosis  DNA repair  History  Vaccine  See also  References  External links  

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