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Align::category    Author::journal    First::title    Reaction::glucose    Pages::volume    Enzyme::synthase

Ribbon diagram of Glucose-6-Phosphate isomerase

Isomerases are a general class of enzymes which convert a molecule from one isomer to another. Isomerases can either facilitate intramolecular rearrangements in which bonds are broken and formed or they can catalyze conformational changes. The general form of such a reaction is as follows:

A–B → B–A

There is only one substrate yielding one product. This product has the same molecular formula as the substrate but differs in bond connectivity or spatial arrangements. Isomerases catalyze reactions across many biological processes, such as in glycolysis and carbohydrate metabolism.


Isomerase sections
Intro  Isomerization  Nomenclature  Classification  Mechanisms of isomerases  The role of isomerase in human disease  Industrial applications  References  External links  

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