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{{ safesubst:#invoke:Unsubst||$N=Merge from |date=__DATE__ |$B= {{#invoke:Message box|mbox}} }} ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily.<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref>

ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L,<ref>{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumor cell proliferation and antiapoptosis.<ref>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref>


ABCE1 sections
Intro   References    External links   

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