::O-succinylbenzoate synthase
::concepts
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o-Succinylbenzoate synthase (OSBS) (EC 4.2.1.113)[1] is an enzyme encoded by the menC gene in E.coli, and catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to form 4-(2'-carboxyphenyl)-4-oxobutyrate, also called o-succinylbenzoate or OSB, hence the name of the enzyme.<ref name=":0">{{#invoke:Citation/CS1|citation
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}}</ref> This reaction is the fourth step in the menaquinone biosynthetic pathway, which is used by bacteria to synthesize menaquinone, also known as vitamin K2.<ref name=":1">{{#invoke:Citation/CS1|citation
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O-succinylbenzoate synthase sections
Intro Classification Menaquinone biosynthetic pathway Structure Activity Homologues in other organisms References
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First::journal Vitamin::reaction Title::pathway Which::enzyme Gerlt::similar Activity::synthase
{{#invoke:Infobox|infobox}}
o-Succinylbenzoate synthase (OSBS) (EC 4.2.1.113)[1] is an enzyme encoded by the menC gene in E.coli, and catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to form 4-(2'-carboxyphenyl)-4-oxobutyrate, also called o-succinylbenzoate or OSB, hence the name of the enzyme.<ref name=":0">{{#invoke:Citation/CS1|citation
|CitationClass=journal
}}</ref><ref>{{#invoke:Citation/CS1|citation
|CitationClass=journal
}}</ref><ref name=":2">{{#invoke:Citation/CS1|citation
|CitationClass=journal
}}</ref><ref name=":3" /><ref name=":4">{{#invoke:Citation/CS1|citation
|CitationClass=journal
}}</ref> This reaction is the fourth step in the menaquinone biosynthetic pathway, which is used by bacteria to synthesize menaquinone, also known as vitamin K2.<ref name=":1">{{#invoke:Citation/CS1|citation
|CitationClass=journal
}}</ref>
O-succinylbenzoate synthase sections
Intro Classification Menaquinone biosynthetic pathway Structure Activity Homologues in other organisms References
PREVIOUS: Intro | NEXT: Classification |
<< | >> |