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::O-succinylbenzoate synthase

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{{#invoke:Infobox|infobox}} o-Succinylbenzoate synthase (OSBS) (EC 4.2.1.113)[1] is an enzyme encoded by the menC gene in E.coli, and catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to form 4-(2'-carboxyphenyl)-4-oxobutyrate, also called o-succinylbenzoate or OSB, hence the name of the enzyme.<ref name=":0">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref name=":2">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref name=":3" /><ref name=":4">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref> This reaction is the fourth step in the menaquinone biosynthetic pathway, which is used by bacteria to synthesize menaquinone, also known as vitamin K2.<ref name=":1">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref>


O-succinylbenzoate synthase sections
Intro   Classification    Menaquinone biosynthetic pathway    Structure    Activity    Homologues in other organisms    References   

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First::journal    Vitamin::reaction    Title::pathway    Which::enzyme    Gerlt::similar    Activity::synthase

{{#invoke:Infobox|infobox}} o-Succinylbenzoate synthase (OSBS) (EC 4.2.1.113)[1] is an enzyme encoded by the menC gene in E.coli, and catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to form 4-(2'-carboxyphenyl)-4-oxobutyrate, also called o-succinylbenzoate or OSB, hence the name of the enzyme.<ref name=":0">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref name=":2">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref name=":3" /><ref name=":4">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref> This reaction is the fourth step in the menaquinone biosynthetic pathway, which is used by bacteria to synthesize menaquinone, also known as vitamin K2.<ref name=":1">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref>


O-succinylbenzoate synthase sections
Intro   Classification    Menaquinone biosynthetic pathway    Structure    Activity    Homologues in other organisms    References   

PREVIOUS: IntroNEXT: Classification
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