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L-Norpseudoephedrine

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L-Norpseudoephedrine, or (−)-norpseudoephedrine, also referable to as (−)-threo-β-hydroxyamphetamine, is a psychostimulant drug of the amphetamine family. It is one of the four optical isomers of phenylpropanolamine, the other three being cathine ((+)-norpseudoephedrine), (−)-norephedrine, and (+)-norephedrine; as well as one of the two enantiomers of norpseudoephedrine (the other, of course, being cathine).<ref name="Macdonald1997">{{#invoke:citation/CS1|citation |CitationClass=book }}</ref> Similarly to cathine, L-norpseudoephedrine acts as a releasing agent of norepinephrine (EC50 = 30 nM) and to a lesser extent of dopamine (EC50 = 294 nM).<ref name="pmid12954796">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref> Due to the 10-fold difference in its potency for inducing the release of the two neurotransmitters however, L-norpseudoephedrine could be called a modestly selective or preferential norepinephrine releasing agent, similarly to related compounds like ephedrine and pseudoephedrine.


L-Norpseudoephedrine sections
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L-Norpseudoephedrine, or (−)-norpseudoephedrine, also referable to as (−)-threo-β-hydroxyamphetamine, is a psychostimulant drug of the amphetamine family. It is one of the four optical isomers of phenylpropanolamine, the other three being cathine ((+)-norpseudoephedrine), (−)-norephedrine, and (+)-norephedrine; as well as one of the two enantiomers of norpseudoephedrine (the other, of course, being cathine).<ref name="Macdonald1997">{{#invoke:citation/CS1|citation |CitationClass=book }}</ref> Similarly to cathine, L-norpseudoephedrine acts as a releasing agent of norepinephrine (EC50 = 30 nM) and to a lesser extent of dopamine (EC50 = 294 nM).<ref name="pmid12954796">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref> Due to the 10-fold difference in its potency for inducing the release of the two neurotransmitters however, L-norpseudoephedrine could be called a modestly selective or preferential norepinephrine releasing agent, similarly to related compounds like ephedrine and pseudoephedrine.


L-Norpseudoephedrine sections
Intro   See also    References   

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