::Field cancerization
::concepts
Longitudinally opened freshly resected colon segment showing a cancer and four polyps. Plus a schematic diagram indicating a likely field defect (a region of tissue that precedes and predisposes to the development of cancer) in this colon segment. The diagram indicates sub-clones and sub-sub-clones that were precursors to the tumors.
Field cancerization (also termed field change, field change cancerization, field carcinogenesis, cancer field effect or premalignant field defect) is a biological process in which large areas of cells at a tissue surface or within an organ are affected by a carcinogenic alteration(s). The process arises from exposure to an injurious environment, often over a lengthy period.<ref name="McGraw-Hill2001"/>
Field cancerization sections
Intro How field cancerization arises Common early carcinogenic alterations Pattern of alterations in a field defect References External links
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Field cancerization (also termed field change, field change cancerization, field carcinogenesis, cancer field effect or premalignant field defect) is a biological process in which large areas of cells at a tissue surface or within an organ are affected by a carcinogenic alteration(s). The process arises from exposure to an injurious environment, often over a lengthy period.<ref name="McGraw-Hill2001"/>
Field cancerization sections
Intro How field cancerization arises Common early carcinogenic alterations Pattern of alterations in a field defect References External links
| PREVIOUS: Intro | NEXT: How field cancerization arises |
| << | >> |