Actions

::Field cancerization

::concepts



Longitudinally opened freshly resected colon segment showing a cancer and four polyps. Plus a schematic diagram indicating a likely field defect (a region of tissue that precedes and predisposes to the development of cancer) in this colon segment. The diagram indicates sub-clones and sub-sub-clones that were precursors to the tumors.

Field cancerization (also termed field change, field change cancerization, field carcinogenesis, cancer field effect or premalignant field defect) is a biological process in which large areas of cells at a tissue surface or within an organ are affected by a carcinogenic alteration(s). The process arises from exposure to an injurious environment, often over a lengthy period.<ref name="McGraw-Hill2001"/>


Field cancerization sections
Intro  How field cancerization arises  Common early carcinogenic alterations  Pattern of alterations in a field defect   References    External links   

PREVIOUS: IntroNEXT: How field cancerization arises
<<>>
Journal::field    Cancer::pages    Title::volume    Author::issue    Field::colon    Repair::cancer

Longitudinally opened freshly resected colon segment showing a cancer and four polyps. Plus a schematic diagram indicating a likely field defect (a region of tissue that precedes and predisposes to the development of cancer) in this colon segment. The diagram indicates sub-clones and sub-sub-clones that were precursors to the tumors.

Field cancerization (also termed field change, field change cancerization, field carcinogenesis, cancer field effect or premalignant field defect) is a biological process in which large areas of cells at a tissue surface or within an organ are affected by a carcinogenic alteration(s). The process arises from exposure to an injurious environment, often over a lengthy period.<ref name="McGraw-Hill2001"/>


Field cancerization sections
Intro  How field cancerization arises  Common early carcinogenic alterations  Pattern of alterations in a field defect   References    External links   

PREVIOUS: IntroNEXT: How field cancerization arises
<<>>